There are two types of runners in Bottles:
The Wine runner is used for all Environments and is therefore in all bottles created, but also for external prefixes imported into Bottles. We support 3 different runners:
Vaniglia (our runner, available by default in Bottles v3)
Lutris (from Lutris Developers)
Proton-GE (from GloriousEggroll)
Vaniglia (Vanilla) is a clean runner as its name suggests. Apply only wine-staging patches and a modern theme created by Joshua Ashton.
It contains several patches for specific gaming titles support, implements OpenVR support and integrates dxvk (installable on wine from the bottle preferences page).
The Proton runner can be installed from the Bottles Preferences page and choosen on bottle creation selecting the Custom Environment. You can also switch from Wine to Proton at any time by changing your bottle preferences.
You can install new runners by clicking the download button next the runner of your interest.
If you're feeling fearless, you can enable Release Candidates to download and then test premature versions of runners, which may include greater software compatibility at the cost of bugs and possible regressions.
Runners are installed via a community-driven Bottles repository.
If the runner you are looking for is not present, you can add it yourself by opening a Pull Request in the repository, providing the runner manifest.